Clinical Pharmacology

Liverpool ADR Avoidability Assessment Tool (LAAT)

Bracken LE, Nunn AJ, Kirkham JJ, et al. Development of the Liverpool Adverse Drug Reaction Avoidability Assessment Tool. PLoS ONE. 2017;12(1):e0169393.
Pubmed PMID: 28046035
[January 2017] Our online tool was reviewed by the author Dr. Louise Bracken from the Paediatric Medicines Research Unit, Institute in the Park, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom.

Liverpool ADR Causality Assessment Tool (LCAT)

Gallagher RM, Kirkham JJ, Mason JR, et al. Development and inter-rater reliability of the Liverpool adverse drug reaction causality assessment tool. PLoS ONE. 2011;6(12):e28096.
Pubmed PMID: 22194808
[January 2017] Our online tool was reviewed by the authors Prof. Sir Munir Pirmohamed and Dr. Ruairi Gallagher.

Clostridium Difficile Associated Disease Severity Score

Neal MD, Alverdy JC, Hall DE, Simmons RL, Zuckerbraun BS. Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease. Ann Surg. 2011;254(3):423-7.
Pubmed PMID: 21865943

RegiSCAR-Group Diagnosis Score for DRESS

Roujeau, J.C., Allanore, L., Liss, Y. et al. Severe Cutaneous Adverse Reactions to drugs (SCAR): definitions, diagnostic criteria, genetic predisposition. Dermatol Sinica. 2009; 27: 203–209

Drug Interaction Probability Scale (DIPS)

Horn JR, Hansten PD, Chan LN. Proposal for a new tool to evaluate drug interaction cases. Ann Pharmacother. 2007;41(4):674-80.
Pubmed PMID: 17389673

Opioid Risk Tool

Webster LR, Webster RM. Predicting aberrant behaviors in opioid-treated patients: preliminary validation of the Opioid Risk Tool. Pain Med. 2005;6(6):432-42.
Pubmed PMID: 16336480

Mehran Contrast-Induced Nephropathy Risk Score after PCI

Mehran R, Aymong ED, Nikolsky E, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol. 2004;44(7):1393-9.
Pubmed PMID: 15464318

AGEP Score of the EuroSCAR Study Group

Sidoroff A, Halevy S, Bavinck JN, Vaillant L, Roujeau JC. Acute generalized exanthematous pustulosis (AGEP)--a clinical reaction pattern. J Cutan Pathol. 2001;28(3):113-9
Pubmed PMID: 11168761

SCORTEN for Toxic Epidermal Necrolysis

Bastuji-garin S, Fouchard N, Bertocchi M, Roujeau JC, Revuz J, Wolkenstein P. SCORTEN: a severity-of-illness score for toxic epidermal necrolysis. J Invest Dermatol. 2000;115(2):149-53.
Pubmed PMID: 10951229


Danan G, Benichou C. Causality assessment of adverse reactions to drugs--I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries. J Clin Epidemiol. 1993;46(11):1323-30.
Pubmed PMID: 8229110

Naranjo algorithm

Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30(2):239-45.
Pubmed PMID: 7249508
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