Todd et al. 1987
I = (0.2 x SIZE) + STAGE + GRADE where size is in cm, stages A, B and C are coded 1-3 and grade is also coded 1-3.
Stage A: Tumour absent from all three nodes sampled
Stage B: Tumour in low axillary node only
Stage C: Tumour in apical axillary and/or internal mammary node
Histological grade was determined by a modification of the Bloom and Richardson criteria (Elston et al., 1982), under the direction of one pathologist (CWE), and ER content was assayed at the Tenovus Institute, Cardiff, by the dextran coated charcoal method (Maynard & Grifiths, 1979)
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